Comprised of a coalition of federal, state, and local law enforcement agencies, social service entities, a healthcare system, and non-governmental organizations (NGOs), Operation Seminole Saber was a US Marshals Service led effort to combat human trafficking and safely locate the most critically missing/endangered children in the Tampa Bay area. Utilizing best practices from across disciplines, this effort included: a command post staffed by law enforcement, NGO’s and behavioral health professionals that facilitated real time communication about identified children; survivor advocates partnered with law enforcement in the field to immediately offer support; and post recovery care in the form of a Recovery Hub that offered an array of health and behavioral health services in one location. Being able to quickly recover children who have run away, particularly those involved in the child welfare or juvenile justice systems, and to immediately stabilize them upon recovery, is critical to preventing exploitation. To address this, planning meetings included all sectors, and a centralized command post was utilized during the execution phase to facilitate direct, real-time communication between agencies. This ability to quickly and freely share information eliminated barriers and allowed for responses in the field and post recovery to be tailored to each child. This multi-disciplinary collaboration was crucial to success in the field and with post recovery stabilization efforts. Trafficked children experience profound violations of trust, and many carry complex, layered trauma. To address this, the entire recovery process must be survivor-centered, culturally responsive, developmentally appropriate, and uniquely tailored to each child. A Recovery Hub, located in a designated secure wing of a large hospital, offered recovered youth private rooms with showers, food, clothing, hygiene/comfort items, and voluntary access to health and behavioral health screenings. This calm, quiet environment staffed by medical and behavioral health professionals trained in how to treat trafficked children prompted several youths to make disclosures about their health care needs, trafficking situations, and desires for placement. Providing a centralized array of services eliminated the need to transport children to multiple locations for care, reduced trauma and mitigated potential security risks. Offering support both in the field and at the Hub proved to be critical to stabilizing youth, with several of those recovered going on to do well in post recovery placements. In April of 2024, Operation Seminole Saber’s unique model resulted in the safe recovery of 27 children and a case closure rate for law enforcement of 80%. A panel of experts will discuss the planning and execution of this operation, lessons learned, their application to a subsequent operation, best practices, and practical applications for how such a multi-disciplinary approach can be replicated.